SUIVI-REA
Trial question
What is the role of multidisciplinary face-to-face intensivist-led consultations in patients discharged from ICU?
Study design
Multi-center
Open label
RCT
Population
Characteristics of study participants
39.0% female
61.0% male
N = 540
540 patients (211 female, 329 male).
Inclusion criteria: adult patients discharged from ICU.
Key exclusion criteria: ICU admission in the previous year; pre-existing chronic myopathy, psychiatric disorder, or dementia; ICU admission for serious burns, severe brain injury, or suicide; pregnancy.
Interventions
N=268 multidisciplinary consultations (multidisciplinary face-to-face consultation involving an intensivist, a psychologist, and a social worker at ICU discharge and then at 3 and 6 months).
N=272 standard care (standard post-ICU follow-up).
Primary outcome
Poor clinical outcome at 12 months
49.7%
41.2%
49.7 %
37.3 %
24.9 %
12.4 %
0.0 %
Multidisciplinary
consultations
Standard
care
Significant
increase ▲
NNH = 11
Significant increase in poor clinical outcome at 12 months (49.7% vs. 41.2%; OR 1.49, 95% CI 1.04 to 2.13).
Secondary outcomes
No significant difference in death during follow-up (14.9% vs. 11.8%; RR 1.3, 95% CI -1.34 to 3.94).
No significant difference in Hospital Anxiety Depression scale score at 12 months (10 points vs. 9 points; AD 1 points, 95% CI -0.95 to 2.95).
Conclusion
In adult patients discharged from ICU, multidisciplinary consultations were inferior to standard care with respect to poor clinical outcome at 12 months.
Reference
Tarek Sharshar, Lamiae Grimaldi-Bensouda, Shidasp Siami et al. A randomized clinical trial to evaluate the effect of post-intensive care multidisciplinary consultations on mortality and the quality of life at 1 year. Intensive Care Med. 2024 May;50(5):665-677.
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