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Pyrantel

Class
Antihelmintic agents
Subclass
Anthelmintics
Substance name
Pyrantel pamoate
Common formulations
Tablet
Dosage and administration
Adults patients
Treatment of enterobiasis
•
Maintenance: 11 mg/kg PO once, repeated in 2 weeks
•
Maximum: 1,000 mg per day
Indications for use
Labeled indications
Adults
•
Treatment of enterobiasis
Children
•
Treatment of enterobiasis
•
Treatment of pinworm
Pregnancy and breastfeeding
Pregnancy
All trimesters • Australia Category: B2
•
Avoid use. - Use should be avoided when possible.
•
- According to some authorities: This drug should be used during pregnancy only if the benefit outweighs the risk.
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- Some experts suggest that single-dose pyrantel therapy may be given to pregnant women.
Breastfeeding
Acceptable for use during breastfeeding.
Unknown amount excreted in breastmilk.
Unknown drug levels in breastfed infants.
Adverse reactions
Unknown frequency
•
↑ body temperature, ↑ liver enzymes, myasthenia gravis, abdominal pain, diarrhea, dizziness, generalized pruritus, headache, insomnia, loss of appetite, nausea, skin rash, somnolence, vomiting, stridor
Interactions
Drug(s)
Check Interactions
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