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Nystatin

Oral
Topical
Class
Hypolipidemic agents
Subclass
HMG-CoA reductase inhibitors
Generic name
Nystatin
Common formulations
Film-coated tablet
Dosage and administration
Adults patients
Treatment of gastrointestinal candidiasis • Non-esophageal mucus membrane candidiasis
•
500,000-1,000,000 unit(s) PO TID at least 48 hours after clinical cure to prevent relapse
Other off-label uses
•
Prevention of candidiasis
Indications for use
Labeled indications
Adults
•
Treatment of gastrointestinal candidiasis (non-esophageal mucus membrane candidiasis)
Off-label indications
Adults
•
Prevention of candidiasis
Safety risks
Contraindications
Hypersensitivity to nystatin or any of its components
Specific populations
Renal impairment
GFR 0-90 mL/min
•
Use acceptable. No dose adjustment required.
Renal replacement therapy
Any modality
•
Use acceptable. No dose adjustment required.
Hepatic impairment
Any severity
•
Use acceptable. No dose adjustment required.
Pregnancy and breastfeeding
Pregnancy
All trimesters • Australia Category: A
•
Use with caution. Animal reproduction studies have not been conducted with this drug. There are no controlled data in human pregnancy and/or reproductive capacity.
Breastfeeding
Acceptable for use during breastfeeding.
Unknown amount excreted in breastmilk.
Unknown drug levels in breastfed infants.
Adverse reactions
Rare < 0.1%
•
Acute generalized exanthematous pustulosis, tachycardia
Unknown frequency
•
Bronchospasm, cough, diarrhea, dyspepsia, facial sweating, myalgia, nausea, skin rash, vomiting, Stevens-Johnson syndrome, urticaria
Interactions
Drug(s)
Check Interactions
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