Midodrine
Class
Sympathomimetics
Subclass
α-adrenergic receptor agonists
Generic name
Midodrine hydrochloride
Common formulations
Tablet
Dosage and administration
Adults patients
Treatment of orthostatic hypotension
Other off-label uses
Indications for use
Labeled indications
Adults
Off-label indications
Adults
Safety risks
Boxed warnings
Urinary retention
Contraindications
Concomitant use of MAOIs
Coronary artery disease
Pre-existing congestive HF
Warnings and precautions
Exacerbation of glycemic control
Specific populations
Renal impairment
eGFR 20-50 mL/min/1.73 m²
eGFR 10-20 mL/min/1.73 m²
eGFR < 10 mL/min/1.73 m²
Renal replacement therapy
Continuous renal replacement
Intermittent hemodialysis
Peritoneal dialysis
Hepatic impairment
Any severity
Pregnancy and breastfeeding
Pregnancy
All trimesters • Australia Category: C
Breastfeeding
Little information available on breastfeeding safety.
Unknown amount excreted in breastmilk.
Unknown drug levels in breastfed infants.
Adverse reactions
Very common > 10%
Common 1-10%
Rare < 0.1%
Unknown frequency
Interactions
Drug(s)
Check Interactions
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