Maprotiline

Class
Antidepressants
Subclass
Tricyclic antidepressants
Substance name
Maprotiline hydrochloride
Common formulations
Film-coated tablet
Dosage and administration
Adults patients
Major depressive disorder
25-225 mg PO daily
Major depressive disorder
75-225 mg PO daily
Other off-label uses
Treatment of panic disorder
Indications for use
Labeled indications
Adults
Treatment of major depressive disorder
Off-label indications
Adults
Treatment of panic disorder
Pregnancy and breastfeeding
Pregnancy
All trimesters
Use only if clearly needed.
Breastfeeding
Consider alternative agents that may be safer.
Unknown amount excreted in breastmilk.
Unknown drug levels in breastfed infants.
No overt adverse effects reported in breastfed infants.
Some adverse effects on lactation reported.
Interactions
Drug(s)
Check Interactions
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