Ctrl

K

Mannitol

Class
Diuretics
Subclass
Osmotic diuretics
Substance name
Mannitol
Brand names
Osmitrol®
Common formulations
Solution for injection
Dosage and administration
Adults patients
Cerebral edema
•
0.25 g/kg IV q6-8h, administered over 30 minutes
Increased intraocular pressure
•
1.5-2 g/kg IV once, administered over 30 minutes
Intracranial hypertension
•
0.25 g/kg IV q6-8h, administered over 30 minutes
Indications for use
Labeled indications
Adults
•
Treatment of cerebral edema
•
Treatment of increased intraocular pressure
•
Treatment of intracranial hypertension
Adverse reactions
Very common > 10%
•
Pulmonary exacerbations of cystic fibrosis, cough, hemoptysis
Common 1-10%
•
Bronchospasm, ↓ FEV1, lower respiratory tract infections, arthralgia, chest discomfort, dizziness, dyspnea, fever, headache, nasal discharge, nausea, retching, throat irritation, throat pain, vomiting, wheezing
Unknown frequency
•
AKI, acidosis, anaphylaxis, anuria, central nervous system depression, cardiac arrest, coma, compartment syndrome, congestive heart failure, ↓ serum potassium, ↓ serum sodium, dehydration, dehydration, electrolyte imbalance, hypertension, hypervolemia, hypotension, hypotension, hypovolemia, ↑ ICP, ↑ serum potassium, ↑ serum sodium, lethargy, metabolic acidosis, metabolic alkalosis, peripheral edema, phlebitis, pulmonary edema, renal failure, blurred vision, chest pain, confusion, diarrhea, dry mouth, dyspnea, ↑ thirst, injection site reactions, limb pain, low urine output, mania, seizure, rhinitis, shivering, tachycardia, thrombophlebitis, urticaria
Interactions
Drug(s)
Check Interactions
Reset

What did you think about this content?

Create free account

Sign up for free to access the full drug resource