Luspatercept

Class
Erythropoiesis-stimulating agents
Subclass
TGF-β superfamily ligand traps
Substance name
Luspatercept, luspatercept-aamt
Brand names
Reblozyl®
Common formulations
Powder for parenteral solution
Dosage and administration
Adults patients
Anemia in patients with beta thalassemia • Requiring regular RBC transfusions
•
1 mg/kg SC q3 weeks
Myelodysplastic syndrome
•
1 mg/kg SC q3 weeks
Indications for use
Labeled indications
Adults
•
Treatment of anemia in patients with beta thalassemia (requiring regular RBC transfusions)
•
Treatment of myelodysplastic syndrome
Interactions
Drug(s)
Check Interactions
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