Etodolac
Class
Nonsteroidal anti-inflammatory drugs
Subclass
Acetates
Substance name
Etodolac
Common formulations
Tablet
Dosage and administration
Adults patients
Osteoarthritis
Rheumatoid arthritis
Other off-label uses
Indications for use
Labeled indications
Adults
Off-label indications
Adults
Safety risks
Contraindications
A history of or active Gastrointestinal disease including peptic ulcer disease, ulcerative colitis, Gastrointestinal perforation, or Gastrointestinal bleeding
Peri-operative pain in the setting of CABG surgery
Pre-existing conditions such as congestive HF or hypertension
Salicylate hypersensitivity or NSAID hypersensitivity
Warnings and precautions
Cardiac arrhythmias
Exacerbation of anemia
Exacerbation of hematologic disorder
Jaundice
Specific populations
Renal impairment
eGFR 20-50 mL/min/1.73 m²
eGFR 10-20 mL/min/1.73 m²
eGFR < 10 mL/min/1.73 m²
Renal replacement therapy
Continuous renal replacement
Intermittent hemodialysis
Peritoneal dialysis
Hepatic impairment
Any severity
Pregnancy and breastfeeding
Pregnancy
< 20 weeks of gestation
20-30 weeks of gestation
> 30 weeks of gestation
Breastfeeding
Little information available on breastfeeding safety.
Unknown amount excreted in breastmilk.
Unknown drug levels in breastfed infants.
Adverse reactions
Common 1-10%
Unknown frequency
Interactions
Drug(s)
Check Interactions
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