Ctrl

K

Eravacycline

Class
Antibiotics
Subclass
Tetracyclines
Generic name
Eravacycline
Brand names
Xerava®
Common formulations
Powder for parenteral solution
Dosage and administration
Adults patients
Treatment of intra-abdominal infections • Complicated
•
1 mg/kg IV q12h
Indications for use
Labeled indications
Adults
•
Treatment of intra-abdominal infections (complicated)
Pregnancy and breastfeeding
Pregnancy
All trimesters
•
Insufficient evidence. Evidence of fetal harm in animals. Use of tetracycline-class antibacterial agents (including this drug) during the second and third trimester of pregnancy may cause discoloration of deciduous teeth and reversible inhibition of bone growth.
•
If this drug is used during the second or third trimester of pregnancy, the patient should be apprised of the potential harm to the fetus.
Breastfeeding
Do not use during breastfeeding.
Unknown amount excreted in breastmilk.
Unknown drug levels in breastfed infants.
Adverse reactions
Common 1-10%
•
Hypotension, infusion-related reactions, diarrhea, nausea, vomiting, wound dehiscence
Uncommon < 1%
•
Acute pancreatitis, allergic reactions, pancreatic necrosis, pleural effusion
Unknown frequency
•
Acidosis, anaphylaxis, dental enamel hypoplasia, ↑ BUN, ↑ LFTs, ↑ serum phosphate, infections, photosensitivity of skin, pseudomembranous colitis, pseudotumoral soft tissue lesion, tooth abnormalities
Interactions
Drug(s)
Check Interactions
Reset

What did you think about this content?

Create free account

Sign up for free to access the full drug resource