Diphenoxylate hydrochloride

Class
Antidiarrheal agents
Subclass
Synthetic opioids
Substance name
Diphenoxylate hydrochloride
Brand names
Lomotil®
Common formulations
Tablet
Dosage and administration
Adults patients
Treatment of diarrhea
•
5 mg PO QID until initial control of diarrhea has been achieved (not more than 10 days)
Indications for use
Labeled indications
Adults
•
Treatment of diarrhea
•
Adjunctive treatment for diarrhea
Pregnancy and breastfeeding
Pregnancy
All trimesters • Australia Category: C
•
Use only if benefits outweigh potential risks. Evidence of fetal harm in animals.
Breastfeeding
Do not use during breastfeeding.
•
Consider alternative agents that may be safer.
Unknown amount excreted in breastmilk.
Unknown drug levels in breastfed infants.
Interactions
Drug(s)
Check Interactions
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