Bivalirudin
Class
Anticoagulants
Subclass
Direct thrombin inhibitors
Generic name
Bivalirudin
Brand names
Angiomax®
Common formulations
Solution for injection
Dosage and administration
Adults patients
Coronary artery thrombosis, undefined PCI
Thromboembolic complications in patients without heparin-induced thrombocytopenia, undefined cardiopulmonary bypass • Off-label
Other off-label uses
Indications for use
Labeled indications
Adults
Off-label indications
Adults
Safety risks
Contraindications
Hypersensitivity to bivalirudin or any of the product components
Active major bleeding
Warnings and precautions
Bleeding
Subacute stent thrombosis
Thromboembolism
Specific populations
Renal impairment
CrCl > 30 mL/min
CrCl < 30 mL/min
Renal replacement therapy
Continuous renal replacement
Intermittent hemodialysis
Peritoneal dialysis
Hepatic impairment
Any severity
Pregnancy and breastfeeding
Pregnancy
All trimesters • Australia Category: C
Breastfeeding
Little information available on breastfeeding safety.
Unknown amount excreted in breastmilk.
Unknown drug levels in breastfed infants.
Adverse reactions
Very common > 10%
Common 1-10%
Uncommon < 1%
Rare < 0.1%
Unknown frequency
Interactions
Drug(s)
Check Interactions
Reset
What did you think about this content?
Sign up for free to access the full drug resource