Table of contents
Vasospastic angina
What's new
Updated 2024 ESC guidelines for the management of vasospastic angina.
Guidelines
Key sources
The following summarized guidelines for the evaluation and management of vasospastic angina are prepared by our editorial team based on guidelines from the European Society of Cardiology (ESC 2024,2021), the Japanese College of Cardiology (JCC/CVIT/JCS 2023), and the American Heart Association (AHA/ACC 2014).
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Diagnostic investigations
ECG monitoring
As per ESC 2024 guidelines:
Obtain a resting 12-lead ECG recording during angina in patients with suspected vasospastic angina.
B
Consider obtaining ambulatory ST-segment monitoring to identify ST-segment deviation during angina in patients with suspected vasospastic angina and frequent symptoms.
C
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Coronary flow reserve assessment
Coronary CTA
Cardiac MRI
Cardiac PET
Cardiac scintigraphy
Vascular endothelial function testing
Diagnostic procedures
Coronary angiography: as per ACC/AHA 2014 guidelines, obtain coronary angiography (invasive or noninvasive) in patients with episodic chest pain accompanied by transient ST-segment elevation to rule out severe obstructive coronary artery disease.
B
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Coronary provocative testing (general indications)
Coronary provocative testing (ischemia with nonobstructive coronary arteries)
Coronary provocative testing (myocardial infarction with nonobstructive coronary arteries)
Coronary provocative testing (post-PCI)
Intravascular ultrasound/optical coherence tomography
Medical management
CCBs: as per ESC 2024 guidelines, initiate CCBs to control symptoms and to prevent ischemia and potentially fatal complications in patients with isolated vasospastic angina.
A
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Nitrates
Beta-blockers
Statins
Aspirin
Nonpharmacologic interventions
Therapeutic procedures
Intracoronary fasudil administration: as per CVIT/JCC/JCS 2023 guidelines, consider administering intracoronary fasudil in patients with refractory coronary spasm.
C
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ICD