Home

Loading...

Table of contents

Soft tissue sarcoma

Guidelines

Key sources

The following summarized guidelines for the management of soft tissue sarcoma are prepared by our editorial team based on guidelines from the American Society for Radiation Oncology (ASTRO 2021) and the European Society of Medical Oncology (ESMO 2018). ...
Show more

Medical management

General principles
As per ASTRO 2021 guidelines:
Obtain expert pathology and radiology review and multidisciplinary evaluation before initiating treatment in patients with localized STS.
B
Determine the sequencing of surgery and radiotherapy in patients with primary, localized extremity and truncal STS based on multidisciplinary evaluation of patient and tumor characteristics.
B
Create free account

More topics in this section

  • Neoadjuvant chemotherapy

  • Adjuvant chemotherapy

  • Definitive chemotherapy

Therapeutic procedures

Neoadjuvant radiotherapy: as per ASTRO 2021 guidelines, offer neoadjuvant radiotherapy in patients with primary, localized extremity and truncal STS at increased risk for local recurrence, planned to undergo oncologic resection.
A
Show 4 more

More topics in this section

  • Adjuvant radiotherapy

  • Technical considerations for radiotherapy

Surgical interventions

Wide-local excision: as per ASTRO 2021 guidelines, perform oncologic resection, when feasible, in patients with primary, localized extremity and truncal STS undergone an unplanned excision.
B

Specific circumstances

Patients with lung metastasis: as per ESMO 2018 guidelines, perform surgical resection as standard treatment of metachronous (disease-free interval ≥ 1 year), resectable lung metastases without extrapulmonary disease, if complete excision of all lesions is feasible.
B

More topics in this section

  • Patients with desmoid-type fibromatosis