Table of contents
Sickle cell disease
Background
Overview
Guidelines
Key sources
Diagnostic investigations
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Screening for complications (pulmonary hypertension)
Screening for complications (pulmonary disease)
Screening for complications (retinopathy)
Screening for complications (hepatitis C)
Screening for complications (ECG)
Evaluation for avascular necrosis
Medical management
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Management of nonresponse to hydroxyurea
Management of acute complications (vaso-occlusive crisis)
Management of acute complications (acute chest syndrome)
Management of acute complications (stroke)
Management of acute complications (splenic sequestration)
Management of acute complications (priapism)
Management of acute complications (acute renal failure)
Management of chronic complications (proteinuria)
Management of chronic complications (avascular necrosis)
Management of chronic complications (gallstones)
Management of chronic complications (leg ulcers)
Management of pain (acute pain)
Management of pain (chronic pain)
Therapeutic procedures
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Indications for long-term exchange transfusions
Management of long-term exchange transfusion
Technical aspects of transfusion
Perioperative care
Preventative measures
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Prevention of invasive pneumococcal disease
Follow-up and surveillance
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Indications for referral (nephrologist)
Indications for referral (ophthalmologist)
Indications for referral (urologist)