Home

Search

Pathway AI

Account ⋅ Sign Out

Table of contents

Calcium pyrophosphate deposition disease

Key sources
The following summarized guidelines for the evaluation and management of calcium pyrophosphate deposition disease are prepared by our editorial team based on guidelines from the American College of Rheumatology (ACR 2023), the European League Against Rheumatism (EULAR 2022; 2011), and the American College of Radiology (ACR 2017).
1
2
3
4
5

Guidelines

1.Diagnostic investigations

Diagnostic imaging
As per ACR 2017 guidelines:
Obtain radiography (often showing characteristic disease distribution and calcification) as initial imaging in patients with suspected calcium pyrophosphate dihydrate disease.
E
Obtain ultrasound or gradient-recalled echo MRI for the detection of chondrocalcinosis and to complement radiography by showing synovitis and additional osseous findings.
E
Create free account

More topics in this section

  • Screening for chronic infections

2.Medical management

General principles: offer both nonpharmacological and pharmacological modalities for optimal treatment of patients with CPPD, tailored according to:
clinical features (isolated chondrocalcinosis, acute, chronic calcium pyrophosphate crystal inflammatory arthritis, OA with CPPD)
general risk factors (age, comorbidities)
the presence of a predisposing metabolic disorder
B
Show 3 more

More topics in this section

  • Management of acute CPP crystal arthritis

  • Management of chronic CPP crystal arthritis

  • Management of OA with CCPD

3.Preventative measures

Routine immunizations: consider offering high-dose or adjuvanted influenza vaccination, rather than regular-dose influenza vaccination, in ≥ 65 years old patients with rheumatic or musculoskeletal diseases and in 18-65 years old patients with rheumatic or musculoskeletal diseases on immunosuppressive medications.
C
Show 17 more

More topics in this section

  • Prophylaxis for P. jirovecii pneumonia