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Clostridial myonecrosis

Guidelines

Key sources

The following summarized guidelines for the management of clostridial myonecrosis are prepared by our editorial team based on guidelines from the Korean Society of Infectious Diseases (KSID/KDA/KOA/KSC 2017) and the Infectious Diseases Society of America (IDSA 2014).
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Medical management

Antibiotic therapy: as per KDA/KOA/KSC/KSID 2017 guidelines, administer combination therapy with penicillin and clindamycin as the definitive antibiotic therapy.
B
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Therapeutic procedures

Hyperbaric oxygen therapy: as per IDSA 2014 guidelines, do not offer hyperbaric oxygen therapy in patients with gas gangrene because of a lack of benefit and the risk of delayed resuscitation and surgical debridement.
D
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Surgical interventions

Surgical debridement: as per KDA/KOA/KSC/KSID 2017 guidelines, perform early surgical debridement of involved tissue and obtain a continued visual evaluation and remove the infected area.
B
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