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The provided system is designed to classify radiation-induced hemorrhagic cystitis based on clinical signs and findings according to the EORTC/RTOG classification. The classification is interpreted as grades, and the inputs range from mild symptoms to severe conditions, even including death directly due to hemorrhagic cystitis.

The system takes a single input corresponding to a description of clinical signs and findings. Each description corresponds to a specific grade of severity, ranging from Grade 1 to Grade 5, as follows:

1. Slight epithelial atrophy, minor telangiectasia, microscopic hematuria is classified as Grade 1.
2. Moderate frequency, generalized telangiectasia, intermittent macroscopic hematuria is classified as Grade 2.
3. Severe frequency and dysuria, generalized telangiectasia often with petechiae, frequent hematuria with decreased bladder capacity is classified as Grade 3.
4. Necrosis/contracted bladder, severe hemorrhagic cystitis is classified as Grade 4.
5. Death directly due to hemorrhagic cystitis is classified as Grade 5.

The computation process is straightforward:
- The system checks the input against each predefined description.
- If a match is found, it assigns the corresponding grade as the result.
- In case no valid input is provided, it returns a message stating that a selection must be made for the input.

The EORTC/RTOG classification of radiation-induced hemorrhagic cystitis is a clinical tool designed for grading the severity of this condition in patients who have undergone radiation therapy. This classification system aids in the assessment of the patient's condition, guiding therapeutic decisions and facilitating communication among healthcare professionals.

The primary components of this classification system are based on clinical signs and findings, which are categorized into five grades. Grade 1 corresponds to slight epithelial atrophy, minor telangiectasia, and microscopic hematuria. Grade 2 is characterized by moderate frequency, generalized telangiectasia, and intermittent macroscopic hematuria. Grade 3 involves severe frequency and dysuria, generalized telangiectasia often with petechiae, and frequent hematuria with decreased bladder capacity. Grade 4 is defined by necrosis or a contracted bladder, and severe hemorrhagic cystitis. Finally, Grade 5 is assigned when death occurs directly due to hemorrhagic cystitis.

The result is determined by matching the patient's clinical signs and findings to the corresponding grade in the classification system. This provides a clear and standardized way to assess the severity of radiation-induced hemorrhagic cystitis, which can be crucial for determining the appropriate course of treatment and predicting patient prognosis.

The European Organisation for Research and Treatment of Cancer/Radiation Therapy Oncology Group (EORTC/RTOG) classification of radiation-induced hemorrhagic cystitis is a clinical tool designed for grading the severity of this condition in patients who have undergone radiation therapy. This classification system aids in the assessment of the patient's condition, guiding therapeutic decisions and facilitating communication among healthcare professionals.

The primary components of this classification system are based on clinical signs and findings, which are categorized into five grades. Grade 1 corresponds to slight epithelial atrophy, minor telangiectasia, and microscopic hematuria. Grade 2 is characterized by moderate frequency, generalized telangiectasia, and intermittent macroscopic hematuria. Grade 3 involves severe frequency and dysuria, generalized telangiectasia often with petechiae, and frequent hematuria with decreased bladder capacity. Grade 4 is defined by necrosis or a contracted bladder, and severe hemorrhagic cystitis. Finally, Grade 5 is assigned when death occurs directly due to hemorrhagic cystitis.

The result is determined by matching the patient's clinical signs and findings to the corresponding grade in the classification system. This provides a clear and standardized way to assess the severity of radiation-induced hemorrhagic cystitis, which can be crucial for determining the appropriate course of treatment and predicting patient prognosis.

EORTC/RTOG classification of radiation-induced hemorrhagic cystitis

This tool evaluates the severity of hemorrhagic cystitis based on urine findings, determining one of four possible grades. By selecting the description that best matches the urine's appearance, the tool categorizes the condition as follows:

- **Non-visible hematuria** indicates Grade I, representing the mildest form of the condition without visible blood in the urine.
- **Macroscopic hematuria** corresponds to Grade II, where blood is visibly present in the urine.
- **Macroscopic hematuria with small clots** is classified as Grade III, showing noticeable clots along with visible blood.
- **Gross hematuria with clots causing urinary tract obstruction requiring instrumentation for clot evacuation** is assigned Grade IV. This represents the most severe form, where clots have accumulated to the point of blocking urine flow, necessitating medical intervention to clear the obstruction.

Understanding these grades helps in recognizing the severity and potential complications associated with hemorrhagic cystitis, guiding appropriate medical response.

The grading system for hemorrhagic cystitis is a clinical tool designed to categorize the severity of this condition based on urine findings. The primary purpose of this grading system is to facilitate standardized communication among clinicians about the patient's condition, guide treatment decisions, and provide a basis for prognostic considerations.

The grading system is based on four primary components, each corresponding to a specific grade of severity. Grade I is assigned when non-visible hematuria is present. Grade II is designated for cases with macroscopic hematuria. The presence of macroscopic hematuria with small clots elevates the condition to Grade III. The most severe form, Grade IV, is characterized by gross hematuria with clots causing urinary tract obstruction that requires instrumentation for clot evacuation.

The result is determined by the most severe symptom present, with each grade representing an escalating level of severity. This grading system provides a clear, concise method for assessing the severity of hemorrhagic cystitis, aiding in the management and treatment of the condition.

Chemical- and radiation-induced hemorrhagic cystitis

Guidelines

Key sources