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Central disorders of hypersomnolence

Guidelines

Key sources

The following summarized guidelines for the evaluation and management of central disorders of hypersomnolence are prepared by our editorial team based on guidelines from the American Academy of Sleep Medicine (AASM 2021,2018) and the European Academy of Neurology (EAN 2021).
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Diagnostic investigations

Actigraphy: as per AASM 2018 guidelines, consider obtaining actigraphy to monitor total sleep time before testing with the multiple sleep latency test in adult and pediatric patients with suspected central disorders of hypersomnolence.
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Specific circumstances

Patients with narcolepsy, adults: as per AASM 2021 guidelines, offer the following medications for the treatment of excessive daytime sleepiness in adult patients with narcolepsy:
modafinil
pitolisant
sodium oxybate
solriamfetol.
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More topics in this section

  • Patients with narcolepsy (pediatrics)

  • Patients with idiopathic hypersomnia

  • Patients with Kleine-Levin syndrome

  • Patients with neurological diseases

  • Patients with myotonic dystrophy

  • Patients with post-traumatic hypersomnia