Ask AI

Search

Updates

Loading...

Table of contents

Antimicrobial-resistant Gram-negative infections

What's new

Updated 2024 IDSA and 2024 SIS guidelines for the management of antimicrobial-resistant Gram-negative infections.

Guidelines

Key sources

The following summarized guidelines for the management of antimicrobial-resistant Gram-negative infections are prepared by our editorial team based on guidelines from the Infectious Diseases Society of America (IDSA 2024), the Surgical Infection Society (SIS 2024), the European Committee on Infection Control (EUCIC/ESCMID 2023,2019), and the European Society for Microbiology and Infectious Diseases (ESCMID 2021).
1
2
3
4
5

Medical management

General principles: as per ESCMID 2021 guidelines, use optimal antibiotic dosing schemes with attention to side effects, especially with the old antibiotics (polymyxins and aminoglycosides).
E
Show 3 more
Create free account

More topics in this section

  • Management of Enterobacterales infections (ESBL-producing)

  • Management of Enterobacterales infections (AmpC beta-lactamase-producing)

  • Management of Enterobacterales infections (third-generation cephalosporin-resistant)

  • Management of Enterobacterales infections (carbapenem-resistant)

  • Management of P. aeruginosa infections (carbapenem-resistant)

  • Management of P. aeruginosa infections (with difficult-to-treat resistance)

  • Management of A. baumannii infections (carbapenem-resistant)

  • Management of S. maltophilia infections

Perioperative care

Perioperative decolonization, colorectal surgery: as per ESCMID/EUCIC 2023 guidelines, consider obtaining rectal screening to identify extended-spectrum cephalosporin-resistant Enterobacterales carriers before colorectal surgery, according to local epidemiology.
C
Show 2 more

More topics in this section

  • Perioperative decolonization (urologic surgery)

  • Perioperative decolonization (solid organ transplantation)

  • Perioperative decolonization (timing and duration)

Preventative measures

Routine decolonization: as per ESCMID/EUCIC 2019 guidelines, do not offer routine decolonization in third-generation cephalosporin-resistant or carbapenem-resistant Enterobacterales carriers.
D