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WHO criteria for polycythemia vera in women

Major criteria
Hemoglobin > 16 g/dL or hematocrit > 48% or increased RBC mass
Bone marrow biopsy showing hypercellularity for age with trilineage growth, including prominent erythroid, granulocytic, and megakaryocytic proliferation with pleomorphic, mature megakaryocytes
Presence of JAK2 V617F or JAK2 exon 12 mutation
Minor criterion
Subnormal serum EPO level
Diagnostic criteria are not met
Reference
Daniel A Arber, Attilio Orazi, Robert Hasserjian et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood. 2016 May 19;127(20):2391-405.
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