TNM classification for upper urinary tract urothelial cell carcinoma
Tumor classification
Tx: Primary tumor cannot be assessed
T0: No evidence of primary tumor
Ta: Non-invasive papillary carcinoma
Tis: Carcinoma in situ
T1: Tumor invading subepithelial connective tissue
T2: Tumor invading muscularis propria
T3: Tumor invading beyond muscularis into peripelvic fat or renal parenchyma (for renal pelvis) or periureteric fat (for ureter)
T4: Tumour invading adjacent organs or through the kidney into perinephric fat
Lymph node classification
Nx: Regional lymph nodes cannot be assessed
N0: No regional lymph node metastasis
N1: Metastasis in a single lymph node ≤ 2 cm in the greatest dimension
N2: Metastasis in a single lymph node > 2 cm or multiple lymph nodes
Distant metastasis
M0: No distant metastasis
M1: Distant metastasis present
Stage cannot be fully assessed
Reference
Amin, M.B., Edge et al. AJCC Cancer Staging Manual. AJCC. 2017.
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