Ask AI

Search

Updates

Loading...

TNM classification for penile cancer

Tumor classification
Tx: Primary tumor cannot be assessed
T0: No evidence of primary tumor
Tis: Penile carcinoma in situ (intraepithelial neoplasia)
Ta: Noninvasive localized SCC
T1a. Tumor invasion (for glans: lamina propria; for foreskin: dermis, lamina propria, or dartos fascia; for shaft: connective tissue between epidermis and corpora regardless of location) without lymphovascular invasion or perineural invasion and is not high grade (grade 3 or sarcomatoid)
T1b: Tumor invasion (for glans: lamina propria; for foreskin: dermis, lamina propria, or dartos fascia; for shaft: connective tissue between epidermis and corpora regardless of location) with lymphovascular invasion and/or perineural invasion, or is high grade (grade 3 or sarcomatoid)
T2: Tumor invading into corpus spongiosum (either glans or ventral shaft) with or without urethral invasion
T3: Tumor invading into corpora cavernosum (including tunica albuginea) with or without urethral invasion
T4: Tumor invading into adjacent structures (scrotum, prostate, pubic bone)
Lymph node classification
Nx: Regional lymph nodes cannot be assessed
N0: No regional lymph node metastasis
N1: ≤ 2 unilateral inguinal metastases, no extranodal extension
N2: ≥ 3 unilateral inguinal metastases or bilateral metastases
N3: Extranodal extension of lymph node metastases or pelvic lymph node metastases
Metastasis classification
M0: No distant metastasis
M1: Distant metastasis present
Stage cannot be fully assessed
Reference
Amin, M.B., Edge et al. AJCC Cancer Staging Manual. AJCC. 2017.
Open reference URL
Create free account