TNM classification for ovarian, fallopian tube, and primary peritoneal carcinoma
Tumor classification
Tx: Primary tumor cannot be assessed
T0: No evidence of primary tumor
T1a: Tumor limited to one ovary (capsule intact) or fallopian tube surface; no malignant cells in ascites or peritoneal washings
T1b: Tumor limited to one or both ovaries (capsules intact) or fallopian tubes, no tumor on ovarian or fallopian tube surface; no malignant cells in ascites or peritoneal washings
T1c: Tumor limited to one or both ovaries with any of ruptured capsule, tumor on ovarian surface, malignant cells in ascites or peritoneal washings
T2a: Tumor involves one or both ovaries or fallopian tubes with pelvic extension or primary peritoneal cancer, extension and/or implants on uterus and/or fallopian tube and/or ovaries
T2b: Tumor involves one or both ovaries or fallopian tubes with pelvic extension or primary peritoneal cancer, extension to and/or implants on other pelvic tissues
T3a: Microscopic extrapelvic (above the pelvic brim) metastasis, peritoneal involvement with or without positive retroperitoneal lymph nodes
T3b: Macroscopic peritoneal metastasis beyond pelvis ≤ 2 cm in diameter with or without retroperitoneal lymph nodes
T3c: Macroscopic peritoneal metastasis beyond pelvis > 2 cm in diameter with or without metastasis to the retroperitoneal lymph nodes (including the extension of tumor to the capsule of liver and spleen without parenchymal involvement of either organ)
Lymph node classification
Nx: Regional lymph nodes cannot be assessed
N0: No regional lymph node metastasis
N0(i+): isolated tumor cells in regional lymph nodes ≤ 0.2 mm
N1a: Metastasis ≤ 10 mm in greatest dimension
N1b: Metastasis > 10 mm in greatest dimension
Distant metastasis
M0: No distant metastasis
M1a: Pleural effusion with positive cytology
M1b: Liver or splenic parenchymal metastases, metastases to extra-abdominal organs (including inguinal lymph nodes and lymph nodes outside abdominal cavity), transmural involvement of intestine
Stage cannot be fully assessed
Reference
Amin, M.B., Edge et al. AJCC Cancer Staging Manual. AJCC. 2017.
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