The calculator in question is the TNM Classification for Laryngeal Cancer, specifically for the supraglottis. TNM stands for Tumor, Node, Metastasis, a system used to classify malignant tumors. This system is developed by the American Joint Committee on Cancer (AJCC) and the Union for International Cancer Control (UICC).

The TNM Classification for Laryngeal Cancer, Supraglottis, is specifically applicable to patients diagnosed with laryngeal cancer located in the supraglottic region of the larynx. This classification system is used to stage the cancer, which is crucial for determining the most appropriate treatment plan and for predicting patient prognosis.

The clinical utility of this calculator lies in its ability to provide a standardized method for describing the extent of disease progression in laryngeal cancer patients. It takes into account the size and extent of the primary tumor (T), the absence or presence and number of regional lymph nodes involved (N), and the absence or presence of distant metastasis (M).

There are no specific exclusion criteria for the use of the TNM Classification for Laryngeal Cancer, Supraglottis. However, it is not applicable to patients with laryngeal cancer located in

TNM classification for laryngeal cancer, supraglottis

# Criteria
 ## Tumor classification
A. Tx: Primary tumor cannot be assessed
B. Tis: Carcinoma in situ
C. T1: Tumor limited to 1 subsite of supraglottis with normal vocal cord mobility
D. T2: Tumor invading mucosa of > 1 adjacent subsite of supraglottis or glottis or region outside the supraglottis (such as mucosa of the tongue base, vallecula, medial wall of the pyriform sinus) without fixation of the larynx
E. T3: Tumor limited to larynx with vocal cord fixation and/or invading postcricoid area, pre-epiglottic space, paraglottic space, and/or inner cortex of thyroid cartilage
F. T4a: Moderately advanced local disease; tumor invading through the outer cortex of the thyroid cartilage and/or invading tissues beyond the larynx (such as the trachea, soft tissues of the neck including deep extrinsic muscle of the tongue, strap muscles, thyroid, or esophagus)
G. T4b: Very advanced local disease; tumor invading prevertebral space, encasing carotid artery, or invading mediastinal structures
## Lymph node classification
H. Nx: Regional lymph nodes cannot be assessed
I. N0: No regional lymph node metastasis
J. N1: Metastasis in a single ipsilateral lymph node (<= 3 cm in greatest dimension) and no extranodal extension
K. N2: Metastasis in a single ipsilateral lymph node (> 3 cm but <= 6 cm in greatest dimension), or metastases in multiple ipsilateral lymph nodes (none > 6 cm in greatest dimension), or metastases in bilateral or contralateral lymph nodes (none > 6 cm in greatest dimension); no extranodal extension
L. N3: Metastasis in a lymph node (> 6 cm in greatest dimension) and no extranodal extension, or metastasis in any lymph node with clinically overt extranodal extension
## Metastasis classification
M. M0: No distant metastasis
N. M1: Distant metastasis present

# Conditions
- B and I and M
- C and I and M
- D and I and M
- (E and I and M) or ((C or D or E) and J and M)
- (F and (I or J) and M) or ((C or D or E or F) and K and M)
- ((C or D or E or F or G) and L and M) or (G and (H or I or J or K or L) and M)
- (C or D or E or F or G) and (H or I or J or K or L) and N
- true