TNM classification for ciliary body and choroid melanoma
Tumor classification
Tx: Primary tumor cannot be assessed
T0: No evidence of primary tumor
T1a: Tumor size category 1 without ciliary body involvement and extraocular extension
T1b: Tumor size category 1 with ciliary body involvement
T1c: Tumor size category 1 without ciliary body involvement but with extraocular extension ≤ 5 mm in largest diameter
T1d: Tumor size category 1 with ciliary body involvement and extraocular extension ≤ 5 mm in largest diameter
T2a: Tumor size category 2 without ciliary body involvement and extraocular extension
T2b: Tumor size category 2 with ciliary body involvement
T2c: Tumor size category 2 without ciliary body involvement but with extraocular extension ≤ 5 mm in largest diameter
T2d: Tumor size category 2 with ciliary body involvement and extraocular extension ≤ 5 mm in largest diameter
T3a: Tumor size category 3 without ciliary body involvement and extraocular extension
T3b: Tumor size category 3 with ciliary body involvement
T3c: Tumor size category 3 without ciliary body involvement but with extraocular extension ≤ 5 mm in largest diameter
T3d: Tumor size category 3 with ciliary body involvement and extraocular extension ≤ 5 mm in largest diameter
T4a: Tumor size category 4 without ciliary body involvement and extraocular extension
T4b: Tumor size category 4 with ciliary body involvement
T4c: Tumor size category 4 without ciliary body involvement but with extraocular extension ≤ 5 mm in largest diameter
T4d: Tumor size category 4 with ciliary body involvement and extraocular extension ≤ 5 mm in largest diameter
T4e: Any tumor size category with extraocular extension > 5 mm in largest diameter
Lymph node classification
Nx: Regional lymph nodes cannot be assessed
N0: No regional lymph node metastasis
N1a: Metastasis in ≥ 1 regional lymph nodes
N1b: No positive regional lymph nodes, but there are discrete tumor deposits in orbit that are not contiguous to the eye (choroidal and ciliary body)
Metastasis classification
M0: No distant metastasis
M1: Largest diameter of largest metastasis ≤ 3 cm
M1b: Largest diameter of the largest metastasis 3.1-8 cm
M1c: Largest diameter of the largest metastasis ≥ 8.1 cm
Stage cannot be fully assessed
Reference
Amin, M.B., Edge et al. AJCC Cancer Staging Manual. AJCC. 2017.
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