The calculator in question is the International Staging System (ISS) for Asymptomatic Myeloma Prognosis. This scoring system is used specifically for patients diagnosed with asymptomatic (smoldering) multiple myeloma, a type of blood cancer. The ISS for Asymptomatic Myeloma Prognosis helps clinicians to stratify patients into different risk groups based on their serum beta-2 microglobulin and albumin levels. This, in turn, aids in predicting the patient's overall survival and progression to symptomatic disease, thereby guiding treatment decisions. The calculator is not applicable to patients with symptomatic multiple myeloma or other types of blood cancers.

Asymptomatic myeloma prognosis

# Criteria
 ## Bone marrow plasmacytosis
A. >= 10%
B. < 10%
## Serum monoclonal protein
C. >= 3 g/dL
D. < 3 g/dL

# Conditions
- B and C
- A and D
- A and C
- B and D
- true