The GAP index for idiopathic pulmonary fibrosis mortality is a prognostic tool designed to predict one, two, and three-year mortality rates in patients with idiopathic pulmonary fibrosis. The index incorporates four primary components: gender, age, and two pulmonary function tests - forced vital capacity (FVC) and diffusing capacity of the lungs for carbon monoxide (DLCO). Each component is assigned a score based on the patient's characteristics. For gender, males are assigned a higher score. Age is divided into three categories, with older patients receiving higher scores. Predicted FVC and DLCO are also divided into categories, with lower percentages of predicted values receiving higher scores. Patients unable to perform the DLCO test are assigned the highest score for that component. The total score is then used to estimate the patient's mortality risk.
Reference
Brett Ley, Christopher J Ryerson, Eric Vittinghoff et al. A multidimensional index and staging system for idiopathic pulmonary fibrosis. Ann Intern Med. 2012 May 15;156(10):684-91.
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