The French mortality score in thrombotic thrombocytopenic purpura, also known as the MITS score, is a clinical tool designed to predict in-hospital mortality in patients diagnosed with thrombotic thrombocytopenic purpura. The score is calculated based on seven key components: age equal to or greater than 60 years, platelet transfusion, acute or chronic renal failure or need of hemodialysis, myocardial infarction, ischemic stroke, central nervous system hemorrhage, and arterial thrombosis. Each component contributes to the overall score, which ranges from 0 to 7 or more.
The MITS score provides a quantitative measure of mortality risk, with higher scores indicating a greater risk. For instance, a score of 0 corresponds to a 0.72% risk of in-hospital mortality, while a score of 7 or more corresponds to a risk greater than 60%. This scoring system allows clinicians to stratify patients based on their risk and guide clinical decision-making accordingly.
Reference
Ruchika Goel, Karen E King, Clifford M Takemoto et al. Prognostic risk-stratified score for predicting mortality in hospitalized patients with thrombotic thrombocytopenic purpura: nationally representative data from 2007 to 2012. Transfusion. 2016 Jun;56(6):1451-8.
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