The ESSIC diagnostic criteria for bladder pain syndrome, also known as the European Society for the Study of Interstitial Cystitis (ESSIC) criteria, is a clinical calculator used in the diagnosis of bladder pain syndrome (BPS), a chronic bladder condition. This calculator is applicable to patients presenting with persistent or recurrent chronic pelvic pain, pressure, or discomfort perceived to be related to the urinary bladder, accompanied by at least one other urinary symptom such as persistent urge to void or frequency. 

The clinical utility of the ESSIC diagnostic criteria lies in its ability to standardize the diagnosis of BPS, which can be challenging due to the variability of symptoms and lack of definitive diagnostic tests. It helps clinicians to differentiate BPS from other conditions with similar symptoms, such as urinary tract infections or overactive bladder syndrome.

Exclusion criteria for the use of the ESSIC diagnostic criteria include the presence of any other identifiable causes of the symptoms, such as active urinary tract infection, bladder stones, tumors, tuberculosis of the urinary tract, radiation cystitis, and specific neurological diseases.

ESSIC diagnostic criteria for bladder pain syndrome

# Criteria
 A. Chronic pelvic pain, pressure or discomfort in bladder area
B. At least one other urinary symptom, such as persistent urge to void or frequency
C. Exclusion of alternative causes for bladder symptoms
## Cystoscopy findings
D. Not done
E. Normal
F. Glomerulations grade II or III
G. Hunner's lesions
## Biopsy findings
H. Not done
I. Normal
J. Inconclusive
K. Inflammatory infiltrates, granulation tissue, detrusor mastocytosis, or intra-fascicular fibrosis

# Conditions
- not A
- not B
- not C
- D and H
- D and I
- D and J
- D and K
- E and H
- E and I
- E and J
- E and K
- F and H
- F and I
- F and J
- F and K
- G and H
- G and I
- G and J
- G and K
- true