The calculator in question is the Diagnostic Criteria for von Willebrand Disease (vWD). This is a set of criteria used to diagnose von Willebrand Disease, a genetic disorder that is characterized by the inability of blood to clot properly. It is the most common hereditary blood-clotting disorder in humans.

The diagnostic criteria for vWD are applicable to patients who present with symptoms suggestive of a bleeding disorder, such as excessive bleeding or bruising, prolonged bleeding time, or a family history of bleeding disorders. The criteria include laboratory findings such as reduced von Willebrand factor (vWF) antigen levels, reduced vWF activity, and/or abnormal ristocetin cofactor activity.

The clinical utility of this calculator is to aid in the diagnosis of vWD, which can then guide appropriate treatment strategies, including medication, desmopressin, and vWF concentrate therapy. 

There are no specific exclusion criteria for the use of these diagnostic criteria. However, they should be used in conjunction with clinical judgment and other diagnostic tests, as there are other conditions that can cause similar symptoms and laboratory findings.

Diagnostic criteria for von Willebrand disease

# Criteria
 A. History of significant mucocutaneous bleeding
B. von Willebrand factor activity is < 0.3 units/mL

# Conditions
- A and B
- true

The diagnosis and management of von Willebrand disease: a United Kingdom Haemophilia Centre Doctors Organization guideline approved by the British Committee for Standards in Haematology.