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Brigham and Women's Hospital tumor staging for cutaneous squamous cell carcinoma

High-risk factors
Tumor diameter ≥ 2 cm
Poorly differentiated histologic characteristics
Perineural invasion
Tumor invasion beyond the subcutaneous fat (excluding bone invasion)
Bone invasion
T1
Reference
Anokhi Jambusaria-Pahlajani, Peter A Kanetsky, Pritesh S Karia et al. Evaluation of AJCC tumor staging for cutaneous squamous cell carcinoma and a proposed alternative tumor staging system. JAMA Dermatol. 2013 Apr;149(4):402-10.
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