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treating acute gout flare

Answer

The treatment for an acute gout flare involves the use of anti-inflammatory agents, with the choice of agent depending on patient factors and preferences.

First-line therapy

Alternative therapies

  • Interleukin-1 inhibitors: In patients with frequent flares and contraindications to colchicine, NSAIDs, and corticosteroids, the EULAR 2017 guidelines suggest initiating IL-1 inhibitors for the treatment of flares . A study found that canakinumab 150 mg was probably superior to triamcinolone acetonide 40 mg in terms of pain relief, resolution of joint swelling, and achieving a good treatment response at 72 hours following treatment, but was probably associated with an increased risk of adverse events

Effective management of an acute gout flare involves prompt initiation of appropriate anti-inflammatory therapy tailored to the patient's individual factors, such as comorbidities and medication tolerance.

References

1

Gout

Medical management

Guidelines

Anti-inflammatory therapy

Pathway
EULAR 2017