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The drug recommended as primary treatment for osteoporosis and women over the age of 70 is

Answer

The primary treatment recommended for osteoporosis in women over the age of 70 is the use of bisphosphonates. This recommendation is supported by several guidelines:

Bisphosphonates as primary treatment

Other therapeutic options

Treatment duration and re-evaluation

  • The Society of Obstetricians and Gynaecologists of Canada (SOGC) 2022 guidelines recommend initiating bisphosphonates, ideally for up to 5 years, in patients with osteoporosis at intermediate risk of fracture, unless contraindicated. Fracture risk should be re-evaluated after 3–5 years of treatment and a drug holiday should be considered
  • The American College of Obstetricians and Gynecologists (ACOG) 2022 guidelines suggest discontinuing bisphosphonates to allow a drug holiday in low-to-moderate risk patients being stable after 5 years of treatment with oral bisphosphonates or after 3 years of therapy with IV zoledronic acid. Treatment may be continued for longer durations of up to 10 years for oral bisphosphonates or up to 6 years for IV zoledronic acid in patients at high risk of fracture

Bisphosphonates are the primary recommended treatment for osteoporosis in women over the age of 70, with other therapeutic options available based on individual patient needs and contraindications. Treatment duration and re-evaluation are important aspects of the management plan.

References

1

Postmenopausal osteoporosis

Medical management

Guidelines

Antiresorptive and anabolic therapy, bisphosphonates

Pathway
AACE/.../ACE 2020