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ppi side effects

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Proton pump inhibitors (PPIs) are generally perceived to be safe and effective, but like any pharmacologic agent, they have the potential for side effects
4
Abstract

4.

Safety of proton pump inhibitor exposure

PubMed
Highly cited
.

Common side effects

  • Gastrointestinal symptoms: PPIs can cause gastrointestinal symptoms such as nausea, vomiting, diarrhea, and abdominal pain.
  • Headache: Headache is a common side effect associated with PPI use.

Long-term use side effects

Drug interactions

Other potential side effects

In conclusion, while PPIs are generally safe and effective, they can cause a range of side effects, particularly with long-term use. Therefore, it is important to regularly review the ongoing indications for PPI use and consider deprescribing in patients without a definitive indication for chronic use
1
Guidelines

1.

Monitoring for indications

Pathway
AGA 2022

References

1

Deprescribing proton pump inhibitors

Follow-up and surveillance

Guidelines

Monitoring for indications

Pathway
AGA 2022