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There is a well-established connection between miscarriage and antiphospholipid antibodies.
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Disease overview
APS is a systemic autoimmune disease characterized by thrombotic or obstetrical events in the presence of antiphospholipid antibodies. APS is associated with morbidity related to stroke (13%), myocard...
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Thrombophilia evaluation, antiphospholipid syndrome
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Pregnant patients
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Management of antiphospholipid syndrome
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In conclusion, antiphospholipid antibodies are associated with an increased risk of miscarriage, and testing for these antibodies is recommended in patients with recurrent pregnancy loss. Management strategies include the use of anticoagulant therapy and low-dose aspirin.
References
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Recurrent pregnancy loss
Diagnostic investigations
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