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Does Ozempic affect kidney function?

Answer

Semaglutide, a glucagon-like peptide-1 receptor agonist, has been shown to have both protective and potentially adverse effects on kidney function.

Protective effects

Potential adverse effects

Dosage adjustment in renal impairment

In conclusion, semaglutide has demonstrated kidney-protective effects in certain patient populations, but it also carries a risk of acute renal failure and worsening of chronic renal failure. Therefore, careful monitoring of renal function is recommended when initiating or increasing the dose of semaglutide, particularly in patients with severe gastrointestinal reactions.

References

1

Semaglutide PO

Monograph

Risks and precautions

Pathway