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definition, pathophysiology, clinical course, prognosis, risk factors of guillain barre syndrome

Answer

Guillain-Barré Syndrome (GBS) is an acute polyradiculoneuropathy characterized by rapidly progressive, symmetrical weakness of the extremities, often following an infectious event
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Abstract

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Guillain-barr é syndrome: pathogenesis, diagnosis, treatment and prognosis

PubMed
Highly cited
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Pathophysiology

Clinical course

Prognosis

Risk factors

In conclusion, Guillain-Barré Syndrome is a potentially life-threatening post-infectious disease characterized by rapidly progressive, symmetrical weakness and decreased reflexes. Its pathogenesis involves molecular mimicry leading to an autoimmune response against peripheral nerves. The clinical course is typically monophasic, but GBS can result in significant morbidity and mortality, with some patients experiencing long-term disability. Prognosis is influenced by factors such as age, severity at onset, and antecedent infections. Infections are the primary risk factors, with several pathogens implicated in triggering the autoimmune response.

References

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Guillain-Barré syndrome

Classification and risk stratification

Guidelines

Prognosis

Pathway
EAN/.../PNS 2023