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Can you provide an overview of the diagnostic approach for suspected tuberculosis?

Answer

The diagnostic approach for suspected tuberculosis involves a combination of clinical evaluation, imaging studies, and laboratory tests, which vary depending on whether pulmonary or extrapulmonary tuberculosis is suspected.

Pulmonary tuberculosis

Extrapulmonary tuberculosis

Screening for latent tuberculosis

In conclusion, the diagnostic approach for suspected tuberculosis involves a combination of clinical evaluation, imaging studies, and laboratory tests, which vary depending on whether pulmonary or extrapulmonary tuberculosis is suspected. Systematic testing for latent tuberculosis infection is also recommended in certain high-risk groups.

References

1

Pulmonary tuberculosis

Diagnostic investigations

Guidelines

Nucleic acid amplification testing, initial testing

Pathway
WHO 2021