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Ampicillin / sulbactam

Class
Antibiotics
Subclass
Penicillin / β-lactamase inhibitor combination
Substance name
Ampicillin / sulbactam
Brand names
Abelcet®
Contains
Ampicillin
Sulbactam sodium
Common formulations
Powder for parenteral solution
Dosage and administration
Adults patients
Gynecological infections • Serious
•
1.5-3 g IV q6h
SSTIs
•
1.5-3 g IV q6h
Endocarditis • Enterococcal, streptococcal • Off-label
•
3 g IV q6h for 6 weeks if not aminoglycoside resistant; >6 weeks if aminoglycoside resistant
Indications for use
Labeled indications
Adults
•
Treatment of gynecological infections (serious)
•
Treatment of SSTIs
Children
•
Treatment of gynecological infections (caused by E. coli)
•
Treatment of SSTIs
Off-label indications
Adults
•
Treatment of endocarditis (enterococcal, streptococcal)
Pregnancy and breastfeeding
Breastfeeding
Acceptable for use during breastfeeding.
Very low levels in breastfed infants (< 5%).
May potentially cause adverse effects in breastfed infants.
Interactions
Drug(s)
Check Interactions
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