Amphetamine XR
Class
Psychostimulants
Subclass
Amphetamines
Substance name
Amphetamine, amfetamine XR
Brand names
Dyanavel XR®, Adzenys XR-ODT®, Adderall XR®
Contains
Amphetamine sulfate
Dextroamphetamine sulfate
Dextroamphetamine saccharate
Amphetamine aspartate monohydrate
Common formulations
Extended-release tablet, Extended-release oral suspension, Orally disintegrating tablet
See also
Amphetamine salts (Adderall®, Mydayis®)
Dosage and administration
Adults patients
Treatment of ADHD
Indications for use
Labeled indications
Adults
Children
Safety risks
Boxed warnings
Drug abuse, drug misuse, stimulant use disorder
Contraindications
Hypersensitivity to amphetamine or its components
Serious cardiac disease
Concomitant use of MAOIs
Warnings and precautions
Exacerbation of psychosis
Exacerbation of Tourette's syndrome, motor tics, verbal tics
Manic or mixed episodes
Psychosis, mania
Raynaud's phenomenon
Serotonin syndrome
Tachycardia
Weight loss, growth delay
Specific populations
Renal impairment
eGFR 0-90 mL/min/1.73 m²
Renal replacement therapy
Any modality
Hepatic impairment
Any severity
Pregnancy and breastfeeding
Pregnancy
All trimesters
Breastfeeding
Do not use during breastfeeding.
Low excretion in breastmilk (5-25%).
Low levels in breastfed infants (5-25%).
May potentially cause adverse effects in breastfed infants.
No overt adverse effects on lactation reported.
Adverse reactions
Very common > 10%
Common 1-10%
Unknown frequency
Interactions
Drug(s)
Check Interactions
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