Acetaminophen / caffeine / dihydrocodeine
Class
Narcotic analgesics
Subclass
Semisynthetic opioids
Substance name
Acetaminophen / caffeine / dihydrocodeine, paracetamol / caffeine / dihydrocodeine
Brand names
Trezix®
Contains
Acetaminophen
Caffeine
Dihydrocodeine
Common formulations
Capsule
Dosage and administration
Adults patients
Symptomatic relief of pain • Severe, requiring opioids
Indications for use
Labeled indications
Adults
Specific populations
Renal impairment
eGFR 20-50 mL/min/1.73 m²
eGFR 10-20 mL/min/1.73 m²
eGFR < 10 mL/min/1.73 m²
Renal replacement therapy
Continuous renal replacement
Intermittent hemodialysis
Peritoneal dialysis
Pregnancy and breastfeeding
Pregnancy
All trimesters • Australia Category: A, A
Breastfeeding
Consider alternative agents that may be safer.
Unknown amount excreted in breastmilk.
Unknown drug levels in breastfed infants.
May potentially cause adverse effects in breastfed infants.
No overt adverse effects on lactation reported.
Adverse reactions
Rare < 0.1%
Unknown frequency
Interactions
Drug(s)
Check Interactions
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