Table of contents
Amyotrophic lateral sclerosis
What's new
Updated 2023 ACCP guidelines for respiratory management in patients with neuromuscular disorders.
Background
Overview
Guidelines
Key sources
Screening and diagnosis
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Differential diagnosis
Communication of diagnosis
Diagnostic investigations
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Evaluation of respiratory function
Cognitive evaluation
Genetic testing
Screening for venous thrombosis
Respiratory support
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Noninvasive ventilation
Invasive ventilation
Weaning from ventilatory support
Medical management
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Riluzole
Edaravone
Management of sialorrhea (pharmacotherapy)
Management of sialorrhea (oral suction)
Management of sialorrhea (botulinum toxin injection)
Management of sialorrhea (radiotherapy)
Management of sialorrhea (surgery)
Management of dyspnea
Management of excessive bronchial secretions (manually assisted cough)
Management of excessive bronchial secretions (lung volume recruitment)
Management of excessive bronchial secretions (mechanical insufflation-exsufflation)
Management of excessive bronchial secretions (high-frequency chest wall oscillation)
Management of excessive bronchial secretions (home suction device and room humidifier)
Management of excessive bronchial secretions (pharmacotherapy)
Management of pseudobulbar affect
Management of fasciculations
Management of spasticity
Management of muscle cramps
Management of dysarthria
Management of depression and anxiety
Management of insomnia and fatigue
Management of cognitive impairment
Management of venous thrombosis
Therapies with no evidence for benefit
Palliative care
End-of-life care
Nonpharmacologic interventions
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Nutritional support