Table of contents
Glioblastoma
What's new
Added 2022 AANS/CNS, 2021 SNO/EANO, 2018 SEOM, 2016 ASTRO, and 2014 ESMO guidelines for the diagnosis and management of glioblastoma.
Guidelines
Key sources
Screening and diagnosis
Classification and risk stratification
Diagnostic investigations
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Diagnostic imaging
Diagnostic procedures
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Molecular testing (IDH mutation, MGMT promoter methylation, and 1p/19q co-deletion)
Molecular testing (further testing)
Molecular testing (repeat testing)
Medical management
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Management of initial disease (radiotherapy)
Management of initial disease (concomitant chemoradiotherapy)
Management of initial disease (target volumes for radiotherapy)
Management of initial disease (tumor-treating fields)
Management of progressive disease (repeat cytoreductive surgery)
Management of progressive disease (carmustine-impregnated wafers)
Management of progressive disease (repeat radiotherapy)
Management of progressive disease (chemotherapy)
Management of progressive disease (targeted therapy)
Management of symptoms (headache)
Management of symptoms (seizure)
Management of symptoms (fatigue)
Management of symptoms (psychological and cognitive disorders)
Management of symptoms (delirium)
Perioperative care
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Postoperative imaging
Patient education
Follow-up and surveillance
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Surveillance after curative-intent therapy (MRI/MRS)
Surveillance after curative-intent therapy (PET/SPECT)
Management of recurrent disease