Home

Loading...

Table of contents

Wernicke's encephalopathy

Guidelines

Key sources

The following summarized guidelines for the evaluation and management of Wernicke's encephalopathy are prepared by our editorial team based on guidelines from the European Federation of Neurological Societies (EFNS 2010). ...
Show more

Screening and diagnosis

Population at risk: as per EFNS 2010 guidelines, consider the diagnosis of WE in patients at risk for thiamine deficiency, such as patients with alcohol abuse, bariatric surgery, hyperemesis gravidarum, starvation, gastrointestinal tract disease, AIDS, malnutrition, cancer, dialysis-dependent kidney disease, chronic vomiting, stem cell transplantation, or thyroid disease.
E
Create free account

More topics in this section

  • Diagnostic criteria

Diagnostic investigations

Thiamine levels: as per EFNS 2010 guidelines, obtain a blood sample for measurement of total thiamine immediately before administration of thiamine in patients with suspected WE.
E

More topics in this section

  • Brain MRI

Medical management

Thiamine supplementation, patients with suspected or manifest WE: as per EFNS 2010 guidelines, administer intravenous thiamine (200 mg IV q8h) in patients with suspected WE. Initiate thiamine prior to giving any carbohydrates.
B

More topics in this section

  • Thiamine supplementation (patients at risk)

Specific circumstances

Patients post bariatric surgery
As per EFNS 2010 guidelines:
Initiate parenteral thiamine supplementation after bariatric surgery.
E
Monitor thiamine status for at least 6 months after bariatric surgery.
B

More topics in this section

  • Patients dying from WE