Screening and diagnosis

Classification and risk stratification

Perioperative care

Quality improvement

Patient education

Nonpharmacologic interventions

Therapeutic procedures

Respiratory support

Follow-up and surveillance

Specific circumstances

Preventative measures

Medical management

Surgical interventions

Inpatient care

Diagnostic procedures

Diagnostic investigations

Insufficient evidence to make a recommendation.

Strongly favor this test or intervention.

The Tel-Hashomer diagnostic criteria is a clinical calculator used for the diagnosis of Familial Mediterranean Fever (FMF). FMF is a genetic disorder that causes recurrent episodes of fever and inflammation, primarily affecting populations of Mediterranean descent such as Armenians, Arabs, Turks, and Jews. 

The Tel-Hashomer criteria are divided into two categories: major and minor. Major criteria include typical attacks of fever and serositis, response to colchicine treatment, and amyloidosis of AA type without a known cause. Minor criteria include recurrent febrile episodes, erysipelas-like erythema, and a positive family history of FMF. 

The clinical utility of this calculator is to aid in the diagnosis of FMF, particularly in cases where genetic testing is inconclusive or unavailable. It is also used to guide treatment decisions, as a positive diagnosis may warrant the use of colchicine, a drug that can prevent FMF attacks and complications.

There are no specific exclusion criteria for the use of the Tel-Hashomer diagnostic criteria. However, it should be noted that this calculator is less effective in populations where FMF is less common, and it may not be as accurate in diagnosing atypical or milder forms of the disease.

Tel-Hashomer diagnostic criteria for familial Mediterranean fever

# Criteria
 # Major criteria
A. Recurrent febrile episodes with serositis (peritonitis, synovitis, or pleuritis) (+3)
B. AA-type amyloidosis without a predisposing disease (+3)
C. Favorable response to continuous colchicine treatment (+3)
# Minor criteria
D. Recurrent febrile episodes (+1)
E. Erysipelas-like erythema (+1)
F. Familial Mediterranean fever in a first-degree relative (+1)

# Conditions
- score >= 5
- score == 4
- true
- score == 0

The Simplified Livneh Diagnostic Criteria for Familial Mediterranean Fever (FMF) is a clinical calculator used to diagnose Familial Mediterranean Fever, a hereditary inflammatory disorder. This calculator is applicable to individuals of all ages who present with recurrent febrile episodes and are suspected of having FMF, particularly those of Mediterranean descent, including Armenians, Arabs, Turks, and Jews.

The Simplified Livneh Diagnostic Criteria for FMF is clinically useful in identifying patients with FMF, which can help guide appropriate treatment and management strategies. It takes into account factors such as the frequency and duration of fever episodes, presence of specific symptoms like abdominal pain or arthritis, response to colchicine treatment, and family history of FMF.

Exclusion criteria for the use of this calculator include the presence of other conditions that could explain the patient's symptoms, such as infections, malignancies, or other rheumatic diseases. Additionally, it may not be as accurate in populations where FMF is less common.

Simplified Livneh diagnostic criteria for familial Mediterranean fever

# Criteria
 # Major criteria
A. Typical attacks of generalized peritonitis (+2)
B. Typical attacks of unilateral pleuritis or pericarditis (+2)
C. Typical attacks of monoarthritis (hip, knee, ankle) (+2)
D. Typical attacks of fever alone (+2)
E. Incomplete abdominal attacks (+2)
# Minor criteria
E. Incomplete thoracic or articular attacks, or both (+1)
H. Exertional leg pain (+1)
I. Favorable response to colchicine (+1)

# Conditions
- score >= 2
- true
- score == 0

The Yalcinkaya-Ozen's diagnostic criteria is a clinical calculator specifically designed for the diagnosis of Familial Mediterranean Fever (FMF) in children. Familial Mediterranean Fever is a genetic autoinflammatory disorder that causes recurrent fevers and painful inflammation of the abdomen, chest, and joints. This calculator is particularly useful in pediatric populations where FMF is suspected, especially in regions where the disease is prevalent such as the Mediterranean region.

The Yalcinkaya-Ozen's diagnostic criteria includes parameters such as typical clinical symptoms, response to colchicine treatment, and presence of MEFV mutations. It helps clinicians to establish a diagnosis of FMF, particularly in cases where genetic testing is not available or inconclusive. 

The exclusion criteria for the use of this calculator would be the presence of other diseases that can mimic FMF symptoms, such as infections, malignancies, or other rheumatic diseases. Also, it may not be as applicable in populations where FMF is rare.

Yalcinkaya-Ozen's diagnostic criteria for childhood familial Mediterranean fever

# Criteria
 # >= 3 attacks of the following, each lasting 6-72 hours
A. Fever (axillary temperature of > 38 degrees C) (+1)
B. Abdominal pain (+1)
C. Chest pain (+1)
D. Arthritis (+1)
## Family history of familial Mediterranean fever
E. Yes (+1)
F. No (+0)

# Conditions
- score >= 2
- true
- score == 0

Familial Mediterranean fever

Guidelines

Key sources

Screening and diagnosis

Diagnostic investigations

Medical management

Specific circumstances

Follow-up and surveillance