Screening and diagnosis

Classification and risk stratification

Perioperative care

Quality improvement

Patient education

Nonpharmacologic interventions

Therapeutic procedures

Respiratory support

Follow-up and surveillance

Specific circumstances

Preventative measures

Medical management

Surgical interventions

Inpatient care

Diagnostic procedures

Diagnostic investigations

Insufficient evidence to make a recommendation.

Strongly favor this test or intervention.

The calculator in question is the IASLC/ITMIG Staging System for Thymic Epithelial Tumors. The abbreviation IASLC stands for International Association for the Study of Lung Cancer, and ITMIG stands for International Thymic Malignancy Interest Group. This staging system is specifically designed for patients diagnosed with thymic epithelial tumors, a rare type of cancer that develops in the thymus gland.

The clinical utility of this calculator is to stage the disease, which is crucial for determining the most appropriate treatment strategy and for predicting patient prognosis. The IASLC/ITMIG Staging System for Thymic Epithelial Tumors is based on the tumor's size, location, and extent of spread, as well as the patient's overall health status.

There are no specific exclusion criteria for the use of this staging system. However, it is important to note that it is not applicable to other types of thymus or mediastinal tumors, and it should be used in conjunction with other diagnostic and clinical information to guide patient management.

IASLC/ITMIG staging system for thymic epithelial tumors

# Criteria
 ## Tumor classification
A. T1a: Encapsulated or unencapsulated, with or without extension into mediastinal fat
B. T1b: Extension into mediastinal pleura
C. T2: Extension into pericardium
D. T3: Extension into any of the following: lung, brachiocephalic vein, superior vena cava, chest wall, phrenic nerve, or hilar (extrapericardial) pulmonary vessels
E. T4: Extension into any of the following: aorta, arch vessels, main pulmonary artery, myocardium, trachea, or esophagus
## Lymph node classification
F. N0: No regional lymph node metastasis
G. N1: Metastasis in anterior (perithymic) lymph nodes
H. N2: Metastasis in deep intrathoracic or cervical lymph nodes
## Metastasis classification
I. M0: No pleural, pericardial, or distant metastasis
J. M1a: Separate pleural or pericardial nodule
K. M1b: Pulmonary intraparenchymal nodule or distant organ metastasis

# Conditions
- (A or B) and F and I
- C and F and I
- D and F and I
- E and F and I
- ((A or B or C or D or E) and G and I) or ((A or B or C or D or E) and (F or G) and J)
- ((A or B or C or D or E) and H and (I or J)) or ((A or B or C or D or E) and (F or G or H) and K)
- true

The calculator in question is the TNM Classification for Thymic Tumors. TNM stands for Tumor, Node, Metastasis, and it is a globally recognized system used for classifying the extent of spread of cancer. This specific TNM classification is applicable to patients with thymic tumors.

The TNM Classification for Thymic Tumors is used to stage thymic malignancies, which helps in determining the prognosis and potential treatment options for the patient. The 'T' in TNM refers to the size and extent of the main tumor, 'N' refers to the number of nearby lymph nodes that have cancer, and 'M' refers to whether the cancer has metastasized, or spread to other parts of the body.

This calculator is not applicable to patients without a confirmed diagnosis of thymic tumor, or those with other types of thoracic tumors. It is also not suitable for use in pediatric patients, as the TNM classification system is generally used for adult cancers.

TNM classification for thymic tumors

# Criteria
 ## Tumor classification
A. Tx: Primary tumor cannot be assessed
B. T0: No evidence of primary tumor
C. T1a: Tumor encapsulated or extending into the mediastinal fat with no mediastinal pleura involvement
D. T1b: Tumor encapsulated or extending into the mediastinal fat with direct invasion of mediastinal pleura
E. T2: Tumor with direct invasion of the pericardium (either partial or full thickness)
F. T3: Tumor with direct invasion into lung, brachiocephalic vein, superior vena cava, phrenic nerve, chest wall, or extrapericardial pulmonary artery or veins
G. T4: Tumor with invasion into aorta (ascending, arch, or descending), arch vessels, intrapericardial pulmonary artery, myocardium, trachea, or esophagus
## Lymph node classification
H. Nx: Regional lymph nodes cannot be assessed
I. N0: No regional lymph node metastasis
J. N1: Metastasis in anterior (perithymic) lymph nodes
K. N2: Metastasis in deep intrathoracic or cervical lymph nodes
## Metastasis classification
L. M0: No pleural, pericardial, or distant metastasis
M. M1a: Pleural or pericardial metastasis
N. M1b: Pulmonary intraparenchymal or distant organ metastasis

# Conditions
- (C or D) and I and L
- E and I and L
- F and I and L
- G and I and L
- ((C or D or E or F or G) and J and L) or ((C or D or E or F or G) and (I or J) and M)
- ((C or D or E or F or G) and K and (L or M)) or ((C or D or E or F or G) and (I or J or K) and N)
- true

Thymic epithelial tumors

Guidelines

Key sources