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The following summarized guidelines for the management of oral candidiasis are prepared by our editorial team based on guidelines from the Infectious Diseases Society of America (IDSA/CDC/NIH/HIVMA 2023), the Infectious Diseases Society of America (IDSA 2016), and the European Society for Microbiology and Infectious Diseases (ESCMID 2012).
Antifungal therapy: offer any of the following in patients with mild OC:
clotrimazole troches 10 mg 5 times daily for 7-14 days
miconazole mucoadhesive buccal 50 mg tablet applied to the mucosal surface over the canine fossa once daily for 7-14 days
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Pregnant patients: do not use voriconazole, anidulafungin and caspofungin in pregnant patients.
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Patients with denture-related candidiasis
Patients with HIV (prevention)
Patients with HIV (antifungal therapy)
Patients with HIV (management of treatment failure)
Chronic suppressive therapy
Avoid offering chronic suppressive therapy in patients with OC.
Offer fluconazole 100 mg 3 times weekly if chronic suppressive therapy is required in patients with recurrent infection.