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Oral candidiasis

Guidelines

Key sources

The following summarized guidelines for the management of oral candidiasis are prepared by our editorial team based on guidelines from the U.S. Department of Health and Human Services (DHHS 2025), the Infectious Diseases Society of America (IDSA 2016), and the European Society for Microbiology and Infectious Diseases (ESCMID 2012).
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Medical management

Antifungal therapy: as per IDSA 2016 guidelines, offer any of the following in patients with mild OC:
clotrimazole troches 10 mg 5 times daily for 7-14 days
miconazole mucoadhesive buccal 50 mg tablet applied to the mucosal surface over the canine fossa once daily for 7-14 days.
A
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Specific circumstances

Patients with denture-related candidiasis: as per IDSA 2016 guidelines, offer disinfection of the denture in addition to antifungal therapy in patients with denture-related candidiasis.
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More topics in this section

  • Patients with HIV (primary prevention)

  • Patients with HIV (antifungal therapy)

  • Patients with HIV (management of treatment failure)

  • Patients with HIV (secondary prevention)

  • Patients with HIV (pregnant patients)

Preventative measures

Chronic suppressive therapy
As per IDSA 2016 guidelines:
Avoid offering chronic suppressive therapy in patients with OC.
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Offer fluconazole 100 mg 3 times weekly if chronic suppressive therapy is required in patients with recurrent infection.
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