Screening and diagnosis

Classification and risk stratification

Perioperative care

Quality improvement

Patient education

Nonpharmacologic interventions

Therapeutic procedures

Respiratory support

Follow-up and surveillance

Specific circumstances

Preventative measures

Medical management

Surgical interventions

Inpatient care

Diagnostic procedures

Diagnostic investigations

Insufficient evidence to make a recommendation.

Strongly favor this test or intervention.

The Rome IV Diagnostic Criteria for Irritable Bowel Syndrome (IBS) is a clinical calculator used to diagnose IBS, a common gastrointestinal disorder. This calculator is applicable to patients who present with chronic abdominal pain and altered bowel habits, which are the primary symptoms of IBS. 

The Rome IV criteria stipulate that for a diagnosis of IBS, patients must have recurrent abdominal pain, on average, at least 1 day per week in the last 3 months, associated with two or more of the following criteria: related to defecation, associated with a change in frequency of stool, and associated with a change in form (appearance) of stool. These criteria should be fulfilled for the last 3 months with symptom onset at least 6 months before diagnosis.

The clinical utility of this calculator is to provide a standardized, symptom-based approach to diagnose IBS, which can be a challenging condition to diagnose due to the lack of specific biomarkers or imaging findings. It helps clinicians to identify patients with IBS, guide treatment decisions, and potentially avoid unnecessary invasive procedures.

There are no specific exclusion criteria for the use of the Rome IV Diagnostic Criteria for IBS. However, it is important to note that these criteria should be used in conjunction with a thorough medical history and

Rome IV diagnostic criteria for irritable bowel syndrome

# Description:
The Rome IV Diagnostic Criteria for Irritable Bowel Syndrome (IBS) is a clinical calculator used to diagnose IBS, a common gastrointestinal disorder. This calculator is applicable to patients who present with chronic abdominal pain and altered bowel habits, which are the primary symptoms of IBS. 

The Rome IV criteria stipulate that for a diagnosis of IBS, patients must have recurrent abdominal pain, on average, at least 1 day per week in the last 3 months, associated with two or more of the following criteria: related to defecation, associated with a change in frequency of stool, and associated with a change in form (appearance) of stool. These criteria should be fulfilled for the last 3 months with symptom onset at least 6 months before diagnosis.

The clinical utility of this calculator is to provide a standardized, symptom-based approach to diagnose IBS, which can be a challenging condition to diagnose due to the lack of specific biomarkers or imaging findings. It helps clinicians to identify patients with IBS, guide treatment decisions, and potentially avoid unnecessary invasive procedures.

There are no specific exclusion criteria for the use of the Rome IV Diagnostic Criteria for IBS. However, it is important to note that these criteria should be used in conjunction with a thorough medical history and
---
# Inputs:
A. Recurrent abdominal pain (>= 1 day/weeks in the last 3 months) (+4)
B. Pain is related to defecation (+1)
C. Onset of pain associated with a change in stool frequency (+1)
D. Onset of pain associated with a change in stool form (appearance) (+1)
---
# Scoring:
- If score >= 6, then Meets criteria for IBS
- If true, then Criteria not met
- If score == 0, then Please make a selection)

The Modified Marsh Classification is a diagnostic tool used specifically for the histologic findings in patients with suspected celiac disease. This classification system is based on the microscopic examination of small intestinal biopsy specimens. It categorizes the severity of the disease into seven stages (0-3c) based on the degree of intraepithelial lymphocytosis, crypt hyperplasia, and villous atrophy. 

The clinical utility of the Modified Marsh Classification is to provide a standardized method for diagnosing celiac disease and assessing the severity of the condition. It helps clinicians to determine the appropriate treatment plan and monitor the patient's response to a gluten-free diet. 

There are no specific exclusion criteria for the use of the Modified Marsh Classification. However, it should be noted that this classification system is only applicable to patients who have undergone a small intestinal biopsy, which is typically performed when celiac disease is suspected based on clinical symptoms and serological testing.

Modified Marsh classification of histologic findings in celiac disease

# Description:
The Modified Marsh Classification is a diagnostic tool used specifically for the histologic findings in patients with suspected celiac disease. This classification system is based on the microscopic examination of small intestinal biopsy specimens. It categorizes the severity of the disease into seven stages (0-3c) based on the degree of intraepithelial lymphocytosis, crypt hyperplasia, and villous atrophy. 

The clinical utility of the Modified Marsh Classification is to provide a standardized method for diagnosing celiac disease and assessing the severity of the condition. It helps clinicians to determine the appropriate treatment plan and monitor the patient's response to a gluten-free diet. 

There are no specific exclusion criteria for the use of the Modified Marsh Classification. However, it should be noted that this classification system is only applicable to patients who have undergone a small intestinal biopsy, which is typically performed when celiac disease is suspected based on clinical symptoms and serological testing.
---
# Inputs:
## Intraepithelial lymphocytes per 100 enterocytes in jejunum/duodenum
A. < 40
B. > 40

## Crypts
C. Normal
D. Hypertrophic

## Villi
E. Normal
F. Mild atrophic
G. Marked atrophic
H. Absent
---
# Scoring:
- If A and C and E, then Type 0
- If B and C and E, then Type 1
- If B and D and E, then Type 2
- If B and D and F, then Type 3a
- If B and D and G, then Type 3b
- If B and D and H, then Type 3c
- If true, then Classification cannot be fully assessed)

The calculator in question is the Diagnostic Criteria for Celiac Disease, also known as the "Four out of Five Rule". This diagnostic tool is used specifically for patients suspected of having celiac disease, an autoimmune disorder that primarily affects the small intestine.

The clinical utility of this calculator is to aid in the diagnosis of celiac disease. It is based on five criteria: typical symptoms of celiac disease, positive serology, HLA-DQ2 or DQ8 genotypes, histological signs of villous atrophy, and response to a gluten-free diet. A diagnosis of celiac disease is considered when a patient meets at least four out of these five criteria.

There are no specific exclusion criteria for the use of this diagnostic tool. However, it should be noted that this tool is not definitive and should be used in conjunction with other diagnostic methods and clinical judgment. It is also important to remember that not all patients with celiac disease present with typical symptoms, and some may be asymptomatic. Therefore, a high index of suspicion is necessary when using this tool.

Diagnostic criteria for celiac disease (four out of five rule)

# Description:
The calculator in question is the Diagnostic Criteria for Celiac Disease, also known as the "Four out of Five Rule". This diagnostic tool is used specifically for patients suspected of having celiac disease, an autoimmune disorder that primarily affects the small intestine.

The clinical utility of this calculator is to aid in the diagnosis of celiac disease. It is based on five criteria: typical symptoms of celiac disease, positive serology, HLA-DQ2 or DQ8 genotypes, histological signs of villous atrophy, and response to a gluten-free diet. A diagnosis of celiac disease is considered when a patient meets at least four out of these five criteria.

There are no specific exclusion criteria for the use of this diagnostic tool. However, it should be noted that this tool is not definitive and should be used in conjunction with other diagnostic methods and clinical judgment. It is also important to remember that not all patients with celiac disease present with typical symptoms, and some may be asymptomatic. Therefore, a high index of suspicion is necessary when using this tool.
---
# Inputs:
A. Typical symptoms of celiac disease, such as chronic diarrhea, growth faltering or weight loss, and iron-deficiency anemia
B. Positive serum CD-specific IgA class antibodies at high titer
C. HLA-DQ2 or DQ8 genotypes
D. Celiac enteropathy on small intestinal biopsy
E. Response to gluten-free diet
---
# Scoring:
- If (A and B and C and D and E) or (A and B and D and E), then CD diagnosed
- If A and C and D and E, then Seronegative CD
- If B and C and D and E, then Non-classic CD
- If A and B and C and D, then Non-responsive CD
- If A and B and C and E, then Potential CD
- If true, then Diagnostic criteria not met)

Chronic diarrhea

Guidelines

Key sources

Screening and diagnosis

Diagnostic investigations

Medical management

Specific circumstances

Follow-up and surveillance