Screening and diagnosis

Classification and risk stratification

Perioperative care

Quality improvement

Patient education

Nonpharmacologic interventions

Therapeutic procedures

Respiratory support

Follow-up and surveillance

Specific circumstances

Preventative measures

Medical management

Surgical interventions

Inpatient care

Diagnostic procedures

Diagnostic investigations

Insufficient evidence to make a recommendation.

Strongly favor this test or intervention.

The calculator in question is the TNM Classification for Bone Cancer, specifically for the appendicular skeleton, trunk, skull, and facial bones. TNM stands for Tumor, Node, Metastasis. This classification system is used by clinicians to stage different types of cancer, including bone cancer, based on the size and extent of the tumor (T), the involvement of lymph nodes (N), and the presence of distant metastasis (M).

This calculator is applicable to patients who have been diagnosed with bone cancer. It helps in determining the stage of the cancer, which is crucial for planning the appropriate treatment strategy and predicting the patient's prognosis. 

The TNM classification does not have specific exclusion criteria. However, it may not be applicable or accurate in cases where the cancer has spread to multiple distant sites, or in patients with certain rare types of bone cancer. It is also less useful in pediatric patients, as bone cancer in children often behaves differently than in adults.

TNM classification for bone cancer (appendicular skeleton, trunk, skull, and facial bones)

# Description:
The calculator in question is the TNM Classification for Bone Cancer, specifically for the appendicular skeleton, trunk, skull, and facial bones. TNM stands for Tumor, Node, Metastasis. This classification system is used by clinicians to stage different types of cancer, including bone cancer, based on the size and extent of the tumor (T), the involvement of lymph nodes (N), and the presence of distant metastasis (M).

This calculator is applicable to patients who have been diagnosed with bone cancer. It helps in determining the stage of the cancer, which is crucial for planning the appropriate treatment strategy and predicting the patient's prognosis. 

The TNM classification does not have specific exclusion criteria. However, it may not be applicable or accurate in cases where the cancer has spread to multiple distant sites, or in patients with certain rare types of bone cancer. It is also less useful in pediatric patients, as bone cancer in children often behaves differently than in adults.
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# Inputs:
## Tumor classification
A. Tx: Primary tumor cannot be assessed
B. T0: No evidence of primary tumor
C. T1: Tumor <= 8 cm in greatest dimension
D. T2: Tumor > 8 cm in greatest dimension
E. T3: Discontinuous tumors in the primary bone site

## Lymph node classification
F. Nx: Regional lymph nodes cannot be assessed
G. N0: No regional lymph node metastasis
H. N1: Regional lymph nodes metastases present

## Distant metastasis
I. M0: No distant metastasis
J. M1a: Metastasis confined to lung
K. M1b: Metastases in bones or other distant sites

## Histologic grade
L. Gx: Grade cannot be assessed
M. G1: Well differentiated
N. G2: Moderately differentiated
O. G3: Poorly differentiated
P. G4: Undifferentiated
---
# Scoring:
- If C and G and I and (M or N), then Stage IA
- If D and G and I and (M or N), then Stage IB
- If C and G and I and (O or P), then Stage IIA
- If D and G and I and (O or P), then Stage IIB
- If E and G and I and (L or M or N or O or P), then Stage III
- If (C or D or E) and G and (J or K) and (L or M or N or O or P), then Stage IVA
- If ((C or D or E) and H and (I or J or K)) or ((C or D or E) and (G or H) and K) and (L or M or N or O or P), then Stage IVB
- If true, then Stage cannot be fully assessed)

Chordoma

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